Association between the rs2106261 polymorphism in the zinc finger homeobox 3 gene and risk of atrial fibrillation: Evidence from a PRISMA-compliant meta-analysis.
Yue WeiLingjie WangChangjian LinYun XieYangyang BaoQingzhi LuoNing ZhangPublished in: Medicine (2022)
The genetic variant rs2106261 SNP is associated with susceptibility to AF in Caucasian and Asian individuals, with Asian samples showing a stronger association. However, based on the current evidence, no association was found in African samples. Future studies, with larger sample sizes and multiple ethnicities, are still necessary.
Keyphrases
- atrial fibrillation
- genome wide
- systematic review
- meta analyses
- copy number
- case control
- heart failure
- dna methylation
- oral anticoagulants
- randomized controlled trial
- catheter ablation
- direct oral anticoagulants
- gene expression
- percutaneous coronary intervention
- african american
- coronary artery disease
- venous thromboembolism
- genome wide analysis