Gasdermin B, an asthma-susceptibility gene, promotes MAVS-TBK1 signaling and airway inflammation.

Tao LiuSiqi LiuXianliang RuiYe CaoJulian HeckerFeng GuoYihan ZhangLu GongYihan ZhouYuzhen YuNandini KrishnamoorthyniSamuel BatesSung ChunNathan BoyerShuang XuJin-Ah ParkMark A Perrella Bruce David LevyScott T WeissHongmei MouBenjamin A RabyXiaobo Zhou

Published in: The European respiratory journal (2024)

expression and airway inflammation upon respiratory virus infection, thereby conferring asthma risk in risk allele carriers.

Keyphrases

chronic obstructive pulmonary disease
lung function
poor prognosis
allergic rhinitis
genome wide
gene expression
binding protein