Adipocytokines and Insulin Resistance: Their Role as Benign Breast Disease and Breast Cancer Risk Factors in a High-Prevalence Overweight-Obesity Group of Women over 40 Years Old.
Daniel Sat-MuñozBrenda-Eugenia Martínez-HerreraLuis-Aarón Quiroga-MoralesBenjamín Trujillo-HernándezJavier-Andrés González-RodríguezLeonardo-Xicotencatl Gutiérrez-RodríguezCaridad-Aurea Leal-CortésEliseo Portilla-de-BuenBenjamín Rubio-JuradoMario Salazar-PáramoEduardo Gómez-SánchezRaúl Delgadillo-CristernaGabriela-Guadalupe Carrillo-NuñezArnulfo Hernan Nava-ZavalaLuz-Ma-Adriana Balderas-PeñaPublished in: International journal of environmental research and public health (2022)
Adipose tissue is crucial for premalignant and malignant tissue transformation in women with overweight-obesity. The adipocyte-breast epithelium interaction could trigger a malignant transformation in a continuum, starting with BBD as premalignant disease, especially in overweight-obese women.