Increased nerve growth factor expression in the synovial tissues of patients with rotator cuff tears.
Ryo TazawaTomonori KenmokuKentaro UchidaLars Arendt-NielsenNaoshige NaguraMitsufumi NakawakiToshihide MatsumotoGen InoueHiroto TakeuchiTakenori JimboToshiyuki NakazawaMichinari FukudaMasashi TakasoPublished in: Molecular pain (2022)
NGF mRNA and protein levels were elevated in patients with painful RCT compared with those in patients with non-painful RSD, whereas COX-2 levels were comparable in the two patient groups. These findings provide insights into novel potential strategies for clinical management of RCT.