Combined influence of depressive symptoms and systemic inflammation on all-cause and cardiovascular mortality: evidence for differential effects by gender in the English Longitudinal Study of Ageing.
Samantha LawesPanayotes DemakakosAndrew SteptoeGlyn LewisLivia A CarvalhoPublished in: Psychological medicine (2018)
The combination of depressive symptoms and increased inflammation confers a considerable increase in CVD mortality risk for men. These effects appear to be independent, suggesting an additive role.