Prospective Clinical Genomic Profiling of Ewing Sarcoma: ERF and FGFR1 Mutations as Recurrent Secondary Alterations of Potential Biologic and Therapeutic Relevance.
Koichi OguraArielle ElkriefAnita S BowmanRichard P KocheElisa de StanchinaRyma BenayedAudrey MauguenMarissa S MattarInna KhodosPaul A MeyersJohn H HealeyWilliam D TapMeera R HameedAhmet ZehirNeerav N ShuklaCharles L SawyersRohit BoseEmily K SlotkinMarc LadanyiPublished in: JCO precision oncology (2022)
Our findings open avenues to new insights into ES pathobiology and to novel therapeutic approaches in a subset of patients with ES.