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Prospective Clinical Genomic Profiling of Ewing Sarcoma: ERF and FGFR1 Mutations as Recurrent Secondary Alterations of Potential Biologic and Therapeutic Relevance.

Koichi OguraArielle ElkriefAnita S BowmanRichard P KocheElisa de StanchinaRyma BenayedAudrey MauguenMarissa S MattarInna KhodosPaul A MeyersJohn H HealeyWilliam D TapMeera R HameedAhmet ZehirNeerav N ShuklaCharles L SawyersRohit BoseEmily K SlotkinMarc Ladanyi
Published in: JCO precision oncology (2022)
Our findings open avenues to new insights into ES pathobiology and to novel therapeutic approaches in a subset of patients with ES.
Keyphrases
  • rheumatoid arthritis
  • transcription factor
  • minimally invasive
  • single cell
  • copy number
  • gene expression