Independent and combined associations of depressive symptoms and sleep disturbance with chronic pain in community-dwelling older adults.

Takafumi SaitoTao ChenHarukaze YatsugiTianshu ChuXin LiuHiro Kishimoto

Published in: Pain reports (2022)

Our analyses did not reveal a synergistic effect of depressive symptoms and sleep disturbance on chronic pain and its severity, suggesting that most of the effects of depressive symptoms on chronic pain may be mediated by sleep disturbance.

Keyphrases

chronic pain
depressive symptoms
sleep quality
social support
pain management
physical activity
gene expression
dna methylation