Predictive values for different cancers and inflammatory bowel disease of 6 common abdominal symptoms among more than 1.9 million primary care patients in the UK: A cohort study.
Annie HerbertMeena RafiqTra My PhamCristina RenziGary A AbelSarah PriceWilliam T HamiltonIrene PetersenGeorgios LyratzopoulosPublished in: PLoS medicine (2021)
Based on evidence from more than 1.9 million patients presenting in primary care, the findings provide estimated PPVs that could be used to guide specialist referral decisions, considering the PPVs of common abdominal symptoms for cancer alongside that for IBD and their composite outcome (cancer or IBD), taking into account the variable PPVs of different abdominal symptoms for different cancers sites. Jointly assessing the risk of cancer or IBD can better support decision-making and prompt diagnosis of both conditions, optimising specialist referrals or investigations, particularly in women.
Keyphrases
- primary care
- end stage renal disease
- papillary thyroid
- newly diagnosed
- ejection fraction
- chronic kidney disease
- decision making
- peritoneal dialysis
- palliative care
- squamous cell
- prognostic factors
- type diabetes
- childhood cancer
- squamous cell carcinoma
- physical activity
- cross sectional
- insulin resistance
- general practice
- case report