Delineating genotype and parent-of-origin effect on the phenotype in MSH6-associated Lynch syndrome.
Anne-Sophie van der Werf-'t LamMar Rodriguez-GirondoMandy VillasmilCarli M TopsLiselotte van HestHans J P GilleFloor A M DuijkersAnja WagnerEllis EikenboomTom G W LetteboerMirjam M de JongSanne W Bajwa-Ten BroekeFonnet BleekerEncarna B Gomez GarciaMev Dominguez-ValentinPal MøllerManon SuerinkMaartje NielsenPublished in: Genes, chromosomes & cancer (2024)
No evidence of POE was detected in MSH6 families. While RNA expression may be linked to varying risks of EC, further investigation is required to explore this observation.