Involvement of the TNF-α Pathway in TKI Resistance and Suggestion of TNFR1 as a Predictive Biomarker for TKI Responsiveness in Clear Cell Renal Cell Carcinoma.
Hee Sang HwangYun Yong ParkSu-Jin ShinHeounjeong GoJa-Min ParkSun Young YoonJae Lyun LeeYoung Mee ChoPublished in: Journal of Korean medical science (2020)
TNF-α signaling may play a role in TKI resistance, and TNFR1 expression may serve as a predictive biomarker for clinically unfavorable TKI responses in ccRCC.