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Comparison of ERG and SPINK1 expression among incidental and metastatic prostate cancer in Japanese men.

Haruhisa KoideTakahiro KimuraHiroyuki InabaShun SatoKosuke IwataniTakashi YorozuBungo FurusatoYuko KamataJun MikiHiroshi KiyotaHiroyuki TakahashiShin Egawa
Published in: The Prostate (2018)
ERG and SPINK1 expression may not have significant influence on the metastatic behavior of PCa. SPINK1 expression was significantly associated with a shorter time to CRPC in metastatic PCa. The expression profile of ERG and SPINK1 may be a useful predictor for effect of androgen deprivation therapy in patients with metastatic castration-sensitive PCa.
Keyphrases
  • poor prognosis
  • prostate cancer
  • squamous cell carcinoma
  • small cell lung cancer
  • binding protein
  • smoking cessation