Comparison of ERG and SPINK1 expression among incidental and metastatic prostate cancer in Japanese men.

Haruhisa KoideTakahiro KimuraHiroyuki InabaShun SatoKosuke IwataniTakashi YorozuBungo FurusatoYuko KamataJun MikiHiroshi KiyotaHiroyuki TakahashiShin Egawa

Published in: The Prostate (2018)

ERG and SPINK1 expression may not have significant influence on the metastatic behavior of PCa. SPINK1 expression was significantly associated with a shorter time to CRPC in metastatic PCa. The expression profile of ERG and SPINK1 may be a useful predictor for effect of androgen deprivation therapy in patients with metastatic castration-sensitive PCa.

Keyphrases

poor prognosis
prostate cancer
squamous cell carcinoma
small cell lung cancer
binding protein
smoking cessation