Advancing data science in drug development through an innovative computational framework for data sharing and statistical analysis.
Ann-Marie MallonDieter A HäringFrank DahlkePiet AardenSoroosh AfyouniDaniel DelbarreKhaled El EmamHabib GanjgahiStephen GardinerChun Hei KwokDominique M WestEwan StraitonSibylle HaemmerleAdam HuffmanTom HofmannLuke J KellyPeter KruscheMarie-Claude LarameeKarine LheritierGreg LigozioAimee ReadieLuis SantosThomas E NicholsJanice BransonChris HolmesPublished in: BMC medical research methodology (2021)
An informatics framework has been developed to capture clinical trial data into a pipeline of anonymisation, quality control, data exploration, and subsequent integration into a database. Establishing this framework has been integral to the development of analytical tools.