Non-statin lipid-lowering therapy over time in very-high-risk patients: effectiveness of fixed-dose statin/ezetimibe compared to separate pill combination on LDL-C.

Julius L KatzmannFrancesc Sorio-VilelaEugen DornstauderUwe FraasTimo SmieszekSofia ZappacostaUlrich Laufs

Published in: Clinical research in cardiology : official journal of the German Cardiac Society (2020)

Prescription for high-potency statins increased over time. Non-statin LLT were infrequently prescribed by GPs. The reduction in LDL-C when statin and ezetimibe were prescribed in combination was considerably larger for FDC; however, a large proportion of patients still remained with uncontrolled LDL-C levels.

Keyphrases

cardiovascular disease
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
low density lipoprotein
coronary artery disease
prognostic factors
systematic review
patient reported outcomes
fatty acid