Impact of Pathological Stratification on the Clinical Outcomes of Advanced Well-Differentiated/Dedifferentiated Liposarcoma Treated with Trabectedin.
Chiara FabbroniGiovanni FucàFrancesca LigorioElena FumagalliMarta BarisellaPaola ColliniCarlo MorosiAlessandro GronchiAngelo Paolo Dei TosPaolo Giovanni CasaliRoberta SanfilippoPublished in: Cancers (2021)
In this retrospective case series, sensitivity to trabectedin was higher in WDLPS/low-grade DDLPS than in high-grade DDLPS. If confirmed in larger series, grading could represent an effective tool to personalize the treatment with trabectedin in patients with advanced LPS.