A potent multifunctional ZIF-8 nanoplatform developed for colorectal cancer therapy by triple-delivery of chemo/radio/targeted therapy agents.

Sonia IranpourAhmad Reza BahramiMahdieh DayyaniAmir Sh Saljooghi Maryam M Matin

Published in: Journal of materials chemistry. B (2024)

The combination of Apt-PEG-DOX/ZIF-8@GQD with RT as a multimodal therapy approach demonstrated promising potential for the targeted treatment of CRC and enhancing therapeutic effectiveness. The co-delivery of DOX and GQD using this nano-platform holds great promise for improving the outcome of CRC treatment.

Keyphrases

cancer therapy
drug delivery
randomized controlled trial
photodynamic therapy
combination therapy
systematic review
stem cells
squamous cell carcinoma
high throughput
chronic pain
metal organic framework
drug release