IDH1 mutation in human glioma induces chemical alterations that are amenable to optical Raman spectroscopy.
Ortrud UckermannWenmin YaoTareq A JuratliRoberta GalliElke LeipnitzMatthias MeinhardtEdmund KochGabriele SchackertGerald SteinerMatthias KirschPublished in: Journal of neuro-oncology (2018)
Raman spectroscopy constitutes a simple, rapid and safe procedure for determination of the IDH1 mutation that shows great promise for clinically relevant in situ diagnostics.