Insights on Protective Effect of Platelet Rich Plasma and Tadalafil on Testicular Ischemia/Reperfusion Injury in Rats Exposed to Testicular Torsion/Detorsion.
Dalia M Abdel GhaffarZienab Helmy EldkenMohammed S SultanRania M KhalilNoha Hamma SakrHanan EissaSally M SafwatPublished in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology (2024)
PRP's proven anti-inflammatory, antioxidant, and antiapoptotic potentials make it a natural treatment for testicular harm caused by tadalafil. For the first time, it was demonstrated that PRP therapy restored the functionality of the vascular endothelium, specifically the control of E-selectin expression. Combining Td and PRP therapy may be a promising strategy for improving response to PDE5 inhibitors.