Bone Mass Effects of Cross-Sex Hormone Therapy in Transgender People: Updated Systematic Review and Meta-Analysis.
Tayane Muniz FigheraPatrícia Klarmann ZiegelmannThaís Rasia da SilvaPoli Mara SpritzerPublished in: Journal of the Endocrine Society (2019)
Long-term CSHT had a neutral effect on BMD in transgender men. In transgender women, only lumbar spine BMD seemed to be affected after CSHT. This evidence is of low to moderate quality as a result of the observational design of studies, small sample sizes, and variations in hormone therapy protocols.