Declining enrolment and other challenges in IBD clinical trials: Causes and potential solutions.

Mathieu UzzanYoram BouhnikMaria AbreuHarris A AhmadShashi AdsulHilde CarlierMarla DubinskyMatthew GerminaroVipul JairathIrene ModestoEric MortensenNeeraj NarulaEzequiel NeimarkAlessandra OortwijnMarijana ProticDavid T RubinYoung S OhJolanta WicharyLaurent Peyrin-BirouletWalter Reinisch

Published in: Journal of Crohn's & colitis (2023)

This joint effort is proposed as the basis for profound clinical trial transformation triggered by investigative centers, contract research organizations (CROs), sponsors, and regulatory agencies.

Keyphrases

clinical trial
phase ii
health insurance
open label
intellectual disability
transcription factor
double blind
phase iii
study protocol
human health
randomized controlled trial
ulcerative colitis
placebo controlled