Lipid droplet-size mapping in human adipose tissue using a clinical 3T system.

Dominik Weidlich Julius Honecker Christof Böhm Stefan RuschkeDaniela JunkerAnh T VanMarcus R MakowskiChristina HolzapfelMelina Claussnitzer Hans Hauner Dimitrios C Karampinos

Published in: Magnetic resonance in medicine (2021)

The proposed acquisition and parameter-estimation methodology was able to probe restricted diffusion effects in lipid droplets. The methodology was validated using phantoms, and its feasibility in measuring an apparent lipid droplet size was demonstrated ex vivo in white adipose tissue.

Keyphrases

adipose tissue
insulin resistance
fatty acid
single cell
high fat diet
high throughput
endothelial cells
high resolution
type diabetes
metabolic syndrome
quantum dots
living cells
mass spectrometry
diffusion weighted imaging