Foveal macular pigment dip in offspring of age-related macular degeneration patients is inversely associated with omega-3 index.
Grant A RutledgeSteven G PrattStuart P RicherByki HuntjensC Blake PerryGunilla PrattCarla PodellaPublished in: BMC ophthalmology (2020)
The percentage of FMPD in AMD offspring is nearly twice that reported for the general population in the scientific literature. Offspring presenting FMPD had similar AMD genetic risk, but significantly reduced % RBC membrane omega-3 fatty acids and thinner foveas compared with those without FMPD. Our data supports the importance of 'essential fatty' acids as an independent AMD risk factor.
Keyphrases
- age related macular degeneration
- fatty acid
- high fat diet
- end stage renal disease
- optical coherence tomography
- chronic kidney disease
- systematic review
- newly diagnosed
- risk factors
- ejection fraction
- peritoneal dialysis
- genome wide
- gene expression
- electronic health record
- adipose tissue
- patient reported
- case report
- patient reported outcomes
- artificial intelligence
- red blood cell