A systematic review of interleukin-31 inhibitors in the treatment of prurigo nodularis.

Mohammad Ali Nilforooshzadeh Nazila Heidari Yekta Ghane Amirhossein Heidari Arman Hajikarim-Hamedani Seyedayin Hosseini Fariba Jaffary Minou Najar Nobari Pegah Tavakolzadeh Niloufar Najar Nobari

Published in: Inflammopharmacology (2024)

IL-31 inhibitors suggest distinct advantages in improving pruritus, sleep quality, and overall quality of life in subjects with moderate-to-severe PN. Further clinical studies are recommended to compare the effectiveness of these biologics to other therapeutic choices.

Keyphrases

sleep quality
depressive symptoms
randomized controlled trial
systematic review
physical activity
high intensity
early onset
atopic dermatitis