Vaspin deficiency failed to promote the proliferation of BMSCs in osteoarthritis.
Junfeng WangZhongqiang ChenZhenpeng GuanPublished in: International journal of rheumatic diseases (2020)
The findings of this study suggest there was abnormal expression of vaspin in OA bone marrow microenvironment, and vaspin likely had a mediator role in the proliferation of BMSCs, which may work by promoting the activation of the PI3K/AKT signaling pathway.