Preoperative endothelial dysfunction in cutaneous microcirculation is associated with postoperative organ injury after cardiac surgery using extracorporeal circulation: a prospective cohort study.
Stanislas AbrardOlivier FouquetJérémie RiouEmmanuel RineauPierre AbrahamCyril SargentiniYannick BigouChristophe BaufretonSigismond LasockiSamir HenniPublished in: Annals of intensive care (2021)
Patients who postoperatively developed organ injury (SOFA score > 3 at 48 h) had preoperatively a longer time to reach the peak of endothelium-dependent vasodilation. Trial registration Clinical-Trials.gov, NCT03631797. Registered 15 August 2018, https://clinicaltrials.gov/ct2/show/NCT03631797.