Interleukin-6, C-reactive protein, fibrinogen, and risk of recurrence after ischaemic stroke: Systematic review and meta-analysis.
John Joseph McCabeE O'ReillySarah CoveneyR CollinsL HealyJ McManusR MulcahyB MoynihanT CassidyF HsuBradford B WorrallS MurphyM O'DonnellPeter J KellyPublished in: European stroke journal (2021)
Despite evidence suggesting an association between inflammatory markers and post-stroke vascular recurrence, substantial methodological heterogeneity was apparent between studies. Individual-patient pooled analysis and standardisation of methods are needed to determine the prognostic role of blood inflammatory markers and to improve patient selection for randomised trials of inflammatory therapies.