Exercise effects on motor function, manual dexterity, and brain oscillatory activity in individuals with Parkinson's disease: Randomized controlled trial protocol.
Maryela de Oliveira MenachoKevin Pacheco-BarriosAugusto J MendesTatiana de Oliveira SatoFelipe FregniAnna Carolyna Lepesteur GianlorençoPublished in: Physiotherapy research international : the journal for researchers and clinicians in physical therapy (2023)
In this clinical trial, 44 PD patients aged 40-80 years will be randomized in four groups: aerobic training (AT), strength training (ST), task-oriented training (TOT), and waiting list group (CG). The AT group will perform 30 min of a cycle ergometer on 50%-70% of the reserve heart rate. The ST group will use equipment for upper limb muscles and will perform two series of 8-12 repetitions for each exercise, and intensity between 50% and 70% of one maximum repetition will be used. The TOT group will perform a program consisting of three activities to enhance reaching, grasping, and manipulation. All the groups will perform three sessions per week for 8 weeks. We will use the UPDRS Motor function section, Nine-Hole Peg Test, and quantitative electroencephalography to measure motor function, manual dexterity, and brain oscillations, respectively. ANOVA and regression models will be used to compare outcomes within and between groups.
Keyphrases
- heart rate
- randomized controlled trial
- high intensity
- clinical trial
- upper limb
- end stage renal disease
- heart rate variability
- blood pressure
- study protocol
- double blind
- virtual reality
- open label
- white matter
- physical activity
- newly diagnosed
- chronic kidney disease
- placebo controlled
- ejection fraction
- resting state
- peritoneal dialysis
- drug delivery
- phase ii
- phase iii
- systematic review
- high resolution
- prognostic factors
- high frequency
- metabolic syndrome
- skeletal muscle
- multiple sclerosis
- patient reported outcomes
- cerebral ischemia
- blood brain barrier
- patient reported