Sensitivity of Advanced Magnetic Resonance Imaging to Progression over Six Months in Early Spinocerebellar Ataxia.

Thiago Junqueira Ribeiro de Rezende Emilien PetitYoung Woo ParkSophie Tezenas du MontcelJames M JoersJonathan M DuBoisH Moore ArnoldMichal PovazanGuita BananRomain ValabreguePhilipp EhsesJennifer FaberPierrick CoupéChiadi U OnyikePeter B BarkerJeremy D SchmahmannEva-Maria RataiSub H SubramonyThomas H MareciKhalaf O BusharaHenry PaulsonThomas KlockgetherAlexandra DurrTetsuo AshizawaChristophe LengletGülin Öznull null

Published in: Movement disorders : official journal of the Movement Disorder Society (2024)

Diffusion MRI is sensitive to disease progression at very early-stage SCA1 and SCA3 and may provide a >5-fold reduction in sample sizes relative to SARA as endpoint for 6-month-long trials. © 2024 The Author(s). Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.

Keyphrases

magnetic resonance imaging
early stage
contrast enhanced
diffusion weighted imaging
computed tomography
early onset
sentinel lymph node
magnetic resonance
systematic review
squamous cell carcinoma
randomized controlled trial
rectal cancer
neoadjuvant chemotherapy