Is APOE ε4 associated with poorer cognitive outcome following traumatic brain injury? A meta-analysis.

Christine R PadgettMathew J SummersClive E Skilbeck

Published in: Neuropsychology (2016)

This meta-analysis indicates that APOE ε4 does not have a detrimental effect on cognitive performance following TBI. We propose that the relationship between APOE and cognitive function following TBI is complex, and a more-nuanced exploration of APOE genotypes is needed. (PsycINFO Database Record

Keyphrases

traumatic brain injury
cognitive decline
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systematic review
severe traumatic brain injury
mild cognitive impairment
meta analyses
randomized controlled trial
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metabolic syndrome