Reduction in ACE2 expression in peripheral blood mononuclear cells during COVID-19 - implications for post COVID-19 conditions.
Gulrayz AhmedYasir AbdelgadirAmro AbdelghaniPippa SimpsonJody BarbeauDonald BaselChristy S BarriosBrandon A SmithKala F SchilterRupa UdaniHoney V ReddiRodney E WilloughbyPublished in: BMC infectious diseases (2024)
This work elucidates biological and temporal plausibility for ACE2, TIMP1, PIIINP and MMP-9 in the pathogenesis of PCC. Intersection of these independent systems is uncommon and may in part explain the rarity of PCC.