Azadirachtin downregulates the expression of the CREB gene and protein in the brain and directly or indirectly affects the cognitive behavior of the Spodoptera litura fourth-instar larvae.

Deqiang QinYou ZhouPeiwen ZhangBenju LiuQun ZhengZhi Xiang Zhang

Published in: Pest management science (2021)

This study clarified that azadirachtin can affect the cognitive behavior of S. litura and treatment with azadirachtin resulted in a downregulation of gene and protein expression of CREB and its pathway proteins. © 2020 Society of Chemical Industry.

Keyphrases

genome wide
copy number
poor prognosis
genome wide identification
binding protein
signaling pathway
resting state
white matter
dna methylation
functional connectivity
protein protein
small molecule
blood brain barrier