The Genetic Etiology of Parkinson's Disease Does Not Robustly Affect Subthalamic Physiology.

Caroline WeillAkiva GallantHalen Baker ErdmanMuneer Abu SninehEduard LinetskyHagai BergmanZvi IsraelDavid Arkadir

Published in: Movement disorders : official journal of the Movement Disorder Society (2023)

The genetic heterogeneity in PD is not associated with electrophysiological differences. Therefore, similar adaptive DBS algorithms would be applicable to genetically heterogeneous patient populations. © 2023 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.

Keyphrases

deep brain stimulation
genome wide
machine learning
parkinson disease
copy number
single cell
randomized controlled trial
dna methylation
systematic review
genetic diversity
meta analyses