Macrophage-inherited exosome excise tumor immunosuppression to expedite immune-activated ferroptosis.

Duo WangGuanhua QiuXiaoqi ZhuQin WangChunyan ZhuChao FangJunjie LiuKun ZhangYan Liu

Published in: Journal for immunotherapy of cancer (2023)

All these actions accomplish a synergistic antitumor enhancement against tumor progression, thus paving a general route to mitigate ITM, activate immune responses, and magnify ferroptosis.

Keyphrases

cell death
immune response
poor prognosis
cancer therapy
dendritic cells
toll like receptor
drug delivery