HOXA9 is a novel myopia risk gene.

Chung-Ling LiangPo-Yuan HsuCheryl S NgoWei Jie SeowNeerja KarnaniHong PanSeang-Mei SawSuh-Hang Hank Juo

Published in: BMC ophthalmology (2019)

Based on the human, animal and cellular data, the transcription factor HOXA9 may promote the expression of pro-myopia genes and RPE proliferation, which eventually contribute to myopia development.

Keyphrases

transcription factor
genome wide identification
long non coding rna
genome wide
poor prognosis
optic nerve
endothelial cells
long noncoding rna
signaling pathway
electronic health record
copy number
genome wide analysis
dna methylation
dna binding
gene expression
bioinformatics analysis
artificial intelligence