Functional Carbon Quantum Dots for Ocular Imaging and Therapeutic Applications.
Vijay Bhooshan KumarIfat SherSigal Rencus-LazarYgal RotenstreichEhud GazitPublished in: Small (Weinheim an der Bergstrasse, Germany) (2022)
Carbon quantum dots (CDs) are a class of emerging carbonaceous nanomaterials that have received considerable attention due to their excellent fluorescent properties, extremely small size, ability to penetrate cells and tissues, ease of synthesis, surface modification, low cytotoxicity, and superior water dispersion. In light of these properties, CDs are extensively investigated as candidates for bioimaging probes, efficient drug carriers, and disease diagnostics. Functionalized CDs represent a promising therapeutic candidate for ocular diseases. Here, this work reviews the potential use of functionalized CDs in the diagnosis and treatment of eye-related diseases, including the treatment of macular and anterior segment diseases, as well as targeting Aβ amyloids in the retina.
Keyphrases
- quantum dots
- sensitive detection
- induced apoptosis
- energy transfer
- diabetic retinopathy
- high resolution
- optic nerve
- optical coherence tomography
- multidrug resistant
- working memory
- cell cycle arrest
- small molecule
- emergency department
- randomized controlled trial
- systematic review
- cancer therapy
- single molecule
- fluorescence imaging
- climate change
- cell proliferation
- combination therapy
- cataract surgery
- meta analyses
- replacement therapy