Expression dynamics of integrin α2, α3, and αV upon osteogenic differentiation of human mesenchymal stem cells.
Hyun Min LeeSe-Ri SeoJeeseung KimMin Kyu KimHyosun SeoKyoung Soo KimYoung-Joo JangChun Jeih RyuPublished in: Stem cell research & therapy (2020)
These findings suggest that integrin α3 and αV induction is a good indicator of OB differentiation. These findings also shed insight into the expression dynamics of integrins upon osteogenic differentiation of hMSCs and provide the reason why different integrin ligands are required for OB differentiation of hMSCs.