Decompression with or without Fusion in Degenerative Lumbar Spondylolisthesis.
Ivar Magne AustevollErland HermansenMorten W FagerlandKjersti StorheimJens I BroxTore SolbergFrode RekelandEric FranssenClemens WeberHelena BrisbyOliver GrundnesKnut R H AlgaardTordis BökerHasan BanitalebiKari IndrekvamChristian Hellumnull nullPublished in: The New England journal of medicine (2021)
In this trial involving patients who underwent surgery for degenerative lumbar spondylolisthesis, most of whom had symptoms for more than a year, decompression alone was noninferior to decompression with instrumented fusion over a period of 2 years. Reoperation occurred somewhat more often in the decompression-alone group than in the fusion group. (NORDSTEN-DS ClinicalTrials.gov number, NCT02051374.).