Long-term effect of denosumab on bone microarchitecture as assessed by tissue thickness-adjusted trabecular bone score in postmenopausal women with osteoporosis: results from FREEDOM and its open-label extension.
Didier HansMichael R McClungShuang HuangMin KimEnisa ShevrojaMichael McClungPublished in: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA (2023)
, independently of BMD, and shifted more patients to lower fracture-risk categories.
Keyphrases
- bone mineral density
- postmenopausal women
- body composition
- open label
- end stage renal disease
- ejection fraction
- chronic kidney disease
- clinical trial
- newly diagnosed
- optical coherence tomography
- squamous cell carcinoma
- randomized controlled trial
- soft tissue
- radiation therapy
- phase ii
- patient reported outcomes
- bone loss
- phase iii
- study protocol
- rectal cancer