Prognostic value of p53 expression in hormone receptor-positive and human epidermal growth factor receptor 2-negative breast cancer patients receiving neoadjuvant chemotherapy.

Loai Saleh AlbinsaadJisun KimIl Yong ChungBeom Seok KoHee Jeong KimJong Won LeeByung Ho SonSei-Hyun AhnSae Byul Lee

Published in: Breast cancer research and treatment (2021)

High expression of immunohistochemically detected p53 was strongly and significantly associated with decreased OS and BCSS than low p53 expression, suggesting that p53 may be a powerful prognostic factor in HR-positive, HER2-negative breast cancer patients receiving NAC.

Keyphrases

neoadjuvant chemotherapy
poor prognosis
epidermal growth factor receptor
prognostic factors
binding protein
endothelial cells
advanced non small cell lung cancer
transcription factor
long non coding rna
radiation therapy
sentinel lymph node
early stage