High Prevalence of Azole-Resistant Aspergillus fumigatus Among Iranian Cystic Fibrosis Patients: Should We Be Concerned?
Azadeh BandeganiMahdi AbastabarJoobin SharifisoorakiZahra AbtahianNarges VaseghiSadegh KhodavaisyAtefeh FakharianSoheila KhalilzadehMohammad Reza ModaresiIman HaghaniAli AhmadiMona GhazanfariReza ValadanHamid BadaliPublished in: Mycoses (2024)
This study first investigated ARAf isolates in Iranian CF patients. Due to a resistance rate of up to 9%, it is recommended that susceptibility testing of Aspergillus isolates from CF patients receiving antifungal treatment be a part of the routine diagnostic workup. However, extensive multicentre studies with a high volume of CF patients are highly warranted to determine the impact of ARAf on CF patients.
Keyphrases
- cystic fibrosis
- end stage renal disease
- ejection fraction
- newly diagnosed
- prognostic factors
- peritoneal dialysis
- randomized controlled trial
- pseudomonas aeruginosa
- patient reported outcomes
- high resolution
- combination therapy
- chronic obstructive pulmonary disease
- patient reported
- clinical practice
- replacement therapy
- genetic diversity
- high speed