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An Adjudication Protocol for Severe Pneumonia.

Chiagozie O PickensCatherine A GaoJustin BodnerJames M WalterJacqueline M KruserHelen K DonnellyAlvaro DonayreKatie CleppNicole BorkowskiRichard G WunderinkBenjamin D Singernull null
Published in: Open forum infectious diseases (2023)
A comprehensive adjudication protocol to identify clinical end points in severe pneumonia resulted in only moderate interobserver agreement. An adjudicated end point of clinical cure by day 7-8 was associated with more favorable hospital discharge dispositions, suggesting that clinical cure by day 7-8 may be a valid end point to use in adjudication protocols.
Keyphrases
  • randomized controlled trial
  • early onset
  • intensive care unit
  • high intensity
  • extracorporeal membrane oxygenation
  • acute respiratory distress syndrome