Evaluation of the association of anticholinergic burden and delirium in older hospitalised patients - A cohort study comparing 19 anticholinergic burden scales.
Angela E Schulthess-LisibachGiulia GallucciValérie BenelliRamona KälinSven SchulthessPatrick E BeelerChantal CsajkaMonika LuttersPublished in: British journal of clinical pharmacology (2022)
A high anticholinergic burden within 24 hours after admission was significantly associated with incident delirium. Although prospective studies need to confirm these results, discontinuing or substituting drugs with a score of ≥3 at admission might be a targeted intervention to reduce incident delirium.
Keyphrases
- cardiac surgery
- end stage renal disease
- emergency department
- cardiovascular disease
- hip fracture
- newly diagnosed
- randomized controlled trial
- ejection fraction
- chronic kidney disease
- risk factors
- physical activity
- peritoneal dialysis
- prognostic factors
- type diabetes
- acute kidney injury
- patient reported outcomes
- drug delivery
- case control