N-methyl-D-aspartate (NMDA) receptor expression and function is required for early chondrogenesis.

Csaba MattaTamás JuhászJános FodorTibor HajdúÉva KatonaCsilla Szűcs-SomogyiRoland TakácsJudit VágóTamás OláhÁdám BartókZoltan VargaGyorgy PanyiLászló CsernochRóza Zákány

Published in: Cell communication and signaling : CCS (2019)

We propose a key role for NMDARs during the transition of chondroprogenitor cells to cartilage matrix-producing chondroblasts.

Keyphrases

induced apoptosis
poor prognosis
cell cycle arrest
oxidative stress
extracellular matrix
signaling pathway
cell proliferation