NMMHC IIA triggered lipid metabolize reprogramming resulting in vascular endothelial cellular tight junction injury.
Yanni LvDaojun HongLongsheng FuYisong QianPublished in: Molecular biology reports (2022)
Mechanistic studies showed that perturbing reprogramming of lipid composition could enhance tight junction damage, which was mediated by the opposing effects of NMMHC IIA.