Single Cell Analysis of Human Colonoids Exposed to Uranium-Bearing Dust.

Roger AtangaLidia L AppellMyranda N ThompsonFredine T LauerAdrian BrearleyMatthew J CampenEliseo F CastilloJulie G In

Published in: Environmental health perspectives (2024)

These findings highlight the significance of crypt-based proliferative cells and secretory cell differentiation using human colonoids to model major colonic responses to uranium-bearing particulate dust exposure. https://doi.org/10.1289/EHP13855.

Keyphrases

endothelial cells
single cell
induced pluripotent stem cells
induced apoptosis
pluripotent stem cells
health risk
health risk assessment
rna seq
cell cycle arrest
high throughput
climate change
heavy metals