Fatty acid synthase and Ki-67 immunoexpression can be useful for the identification of malignant component in carcinoma ex-pleomorphic adenoma.
Katya Pulido DíazRogério de Oliveira GondakLeandro Liporoni MartinsOslei Paes de AlmeidaJorge Esquiche LeónFernanda Viviane MarianoAlbina AltemaniPablo Agustin VargasPublished in: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology (2019)
The present results suggest that overexpression of FASN in CXPAs might be associated with malignant transformation of ductal epithelial cells and/or myoepithelial cells from PA. FASN associated with Ki-67 may be useful diagnostic markers for CXPA.