Plasma 25-Hydroxyvitamin D Levels and Survival in Patients with Advanced or Metastatic Colorectal Cancer: Findings from CALGB/SWOG 80405 (Alliance).
Chen YuanKaori SatoBruce W HollisSui ZhangDonna NiedzwieckiFang-Shu OuI-Wen ChangBert H O'NeilFederico InnocentiHeinz-Josef LenzCharles D BlankeRichard M GoldbergAlan P VenookRobert J MayerCharles S FuchsJeffrey A MeyerhardtKimmie NgPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2019)
In this large cohort of patients with advanced or metastatic colorectal cancer, higher plasma 25(OH)D levels were associated with improved OS and PFS. Clinical trials assessing the benefit of vitamin D supplementation in patients with colorectal cancer are warranted.