Exposure-response modeling of tocilizumab in rheumatoid arthritis using continuous composite measures and their individual components.
Carla BastidaDolors SoyVirginia Ruiz-EsquideRaimon SanmartíAlwin D R HuitemaPublished in: British journal of clinical pharmacology (2019)
Our study confirms a different dynamics of the individual components of the most frequently used continuous composite measures under tocilizumab treatment which should be taken into account to avoid misassessment of disease activity.