Epidemiology and Molecular Profile of Mucosal Melanoma: A Population-Based Study in Southern Europe.

Anna Carbó-BaguéJordi Rubio Casadevall Montserrat Puigdemont Arantza SanvisensGlòria OliverasMònica CollBernat Del OlmoFerran Perez-BuenoRafael Marcos-Gragera

Published in: Cancers (2022)

Our study confirms the steady incidence and low survival of mucosal melanomas in a region of southern Europe. NRAS and NF1 play a role in the molecular landscape of mucosal melanoma. MEK and PI3K/mTOR inhibitors could be reasonable treatment options and are being studied in clinical trials.

Keyphrases

clinical trial
ulcerative colitis
risk factors
signaling pathway
pi k akt
single molecule
oxidative stress
lps induced
single cell
nuclear factor
inflammatory response
randomized controlled trial
immune response
open label
study protocol
solid state
wild type