Corneal sub-basal nerve plexus assessment and its association with phenotypic features and lymphocyte subsets in Sjögren's Syndrome.
Filipe BarcelosCarlos Diogo Hipólito-FernandesCatarina Gregório MartinsMiguel Ângelo-DiasJoana CardigosRicardo MonteiroNuno AlvesJosé Vaz-PattoJaime C BrancoLuís-Miguel BorregoPublished in: Acta ophthalmologica (2021)
This is the first study aiming to correlate ocular findings with lymphocyte subsets in SjS. The associations founded between CNFL and CNFD and disease activity, IL21+ follicular T cells and some B-cell subsets suggest that corneal nerve damage may parallel systemic disease activity and inflammatory cells' dynamics.
Keyphrases
- disease activity
- peripheral blood
- systemic lupus erythematosus
- rheumatoid arthritis
- rheumatoid arthritis patients
- ankylosing spondylitis
- juvenile idiopathic arthritis
- induced apoptosis
- oxidative stress
- optical coherence tomography
- cell cycle arrest
- wound healing
- peripheral nerve
- case report
- ultrasound guided
- endoplasmic reticulum stress
- cataract surgery
- drug induced
- optic nerve