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Corneal sub-basal nerve plexus assessment and its association with phenotypic features and lymphocyte subsets in Sjögren's Syndrome.

Filipe BarcelosCarlos Diogo Hipólito-FernandesCatarina Gregório MartinsMiguel Ângelo-DiasJoana CardigosRicardo MonteiroNuno AlvesJosé Vaz-PattoJaime C BrancoLuís-Miguel Borrego
Published in: Acta ophthalmologica (2021)
This is the first study aiming to correlate ocular findings with lymphocyte subsets in SjS. The associations founded between CNFL and CNFD and disease activity, IL21+ follicular T cells and some B-cell subsets suggest that corneal nerve damage may parallel systemic disease activity and inflammatory cells' dynamics.
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