CTCF and cohesin promote focal detachment of DNA from the nuclear lamina.
Tom van SchaikNing Qing LiuStefano G ManzoDaan Peric-HupkesElzo de WitBas van SteenselPublished in: Genome biology (2022)
These findings illustrate that CTCF and cohesin are not primary determinants of LAD patterns. Rather, these proteins locally modulate NL interactions.